Supplements For Psoriasis

Living with psoriasis can be frustrating, not only because of the visible symptoms like redness, flaking, and itching, but also because of the underlying inflammation driving the condition. While there’s no single cure for this autoimmune condition, the right supplements for psoriasis can help support your skin from the inside out. By addressing inflammation, strengthening your immune system, and aiding detoxification, you can help your skin find its way back to balance.

 

Why Supplements Matter For Psoriasis

Psoriasis is more than a skin-deep problem; it’s an autoimmune condition that causes skin cells to multiply too quickly. This rapid turnover leads to scaling, redness, and discomfort. 

At its core, psoriasis involves inflammation, immune system imbalances, and oxidative stress. Supplements can help by targeting these root causes, giving your body the support it needs to restore skin health naturally.

High-quality psoriasis relief supplements often contain compounds that help enhance detoxification, minimize inflammation, and support gut restoration, three areas shown to have a direct link to skin health. 

For those seeking natural remedies for psoriasis, these supplements can complement other treatments and lifestyle changes to deliver more consistent, lasting improvements.

Key Ingredients in Effective Psoriasis Supplements

When choosing psoriasis supplements, look for clinically studied ingredients that work on multiple levels, reducing inflammation, supporting detoxification, and strengthening skin cell resilience.

Sulforaphane For Inflammation Control

Sulforaphane, naturally found in broccoli seeds and sprouts, is a powerful plant compound that activates NRF2, a master regulator of the body’s antioxidant and detox pathways. It’s been clinically studied for its ability to help enhance detoxification, minimize inflammation, and support gut restoration, all key factors in managing psoriasis symptoms.

Looking for the best sulforaphane supplement? Broc Shot’s formula delivers bioactive natural sulforaphane in an easy-to-take shot for daily skin and immune support.

Antioxidants For Skin Resilience

When you get antioxidants through your diet or supplements, they work from the inside out to protect your skin cells against oxidative stress and everyday damage. Nutrients like vitamin C, vitamin E, green tea catechins, and plant polyphenols strengthen your body’s natural defenses. By calming inflammation and easing irritation, they can help keep redness down and support a healthier, more resilient skin barrier.

Broccoli-Derived Compounds For Detox Support

Broccoli contains glucoraphanin and the enzyme myrosinase, which combine to form active sulforaphane. Supplements like broccoli powder and broccoli supplements make it easier to get consistent doses of these beneficial compounds without daily food prep.

Sulforaphane For Skin Health

Sulforaphane’s skin benefits extend beyond inflammation control; it also helps promote detoxification and protect against UV-related damage. Studies on sulforaphane benefits for skin highlight its ability to support healthy skin cell function, improve resilience against environmental stressors, and maintain a clearer, more even complexion over time.

Gut Health, Supplements, and Psoriasis

Your gut is more than just a digestive organ. It’s also a central hub for immune regulation and inflammation control. Research increasingly shows that imbalances in the gut microbiome, known as dysbiosis, can contribute to autoimmune conditions like psoriasis. When the gut lining becomes compromised, inflammatory molecules can enter the bloodstream, triggering immune overreactions that accelerate skin cell turnover and lead to flare-ups.

Supplements that support gut restoration, such as natural sulforaphane, help strengthen the intestinal barrier, promote beneficial bacteria growth, and reduce the immune overreactions that can lead to psoriasis symptoms. 

By nourishing the gut environment and supporting its protective functions, sulforaphane works on one of the core drivers of psoriasis. A healthy gut environment can lead to fewer flare-ups, calmer skin, and better long-term symptom control.

Gut health strategies for psoriasis relief include:

  • Incorporate prebiotic-rich foods like garlic, onions, and asparagus to feed beneficial gut bacteria.
  • Add probiotic or fermented foods such as yogurt, kimchi, or kefir to help restore microbial diversity.
  • Prioritize dietary fiber from vegetables, legumes, and whole grains to keep digestion and elimination regular.
  • Limit processed and inflammatory foods, which can disrupt the gut lining and fuel harmful bacteria.
  • Use targeted supplements like natural sulforaphane to help enhance detoxification, minimize inflammation, and support gut restoration.
Original Broc Shot

How to Choose the Right Supplements For Psoriasis

Selecting the right supplement can make a big difference in symptom relief. Look for products with standardized, active nutrient levels so you know exactly what you’re getting. Ensure they’re third-party tested for purity and potency, and free from contaminants like pesticides and heavy metals.

Choose supplements that provide bioactive forms of nutrients that your body can use immediately. For example, sulforaphane in its active form delivers more targeted benefits than its inactive precursors. Avoid products with unnecessary additives that could trigger additional skin sensitivity.

The Science Of Sulforaphane and Broccoli Seeds

The power of sulforaphane begins in the broccoli seed, where glucoraphanin is stored in high concentrations. When combined with the enzyme myrosinase, glucoraphanin transforms into bioactive natural sulforaphane: the form your body can use. This compound has been clinically studied for its ability to help enhance detoxification, minimize inflammation, and support gut restoration.

By activating NRF2, sulforaphane triggers the production of antioxidant and detox enzymes, helping to strengthen your skin’s defense system from the inside out. This is especially valuable for those with psoriasis, as it addresses inflammation at a cellular level. See more about sulforaphane’s cancer-preventive research here: broccoli sprouts cancer.

Combining Supplements For Maximum Benefit

Sulforaphane works well when combined with other targeted nutrients. Green tea catechins offer additional antioxidant support, vitamin C helps repair skin tissue, and omega-3 fatty acids reduce inflammatory signaling. Together, these compounds create a strong foundation for psoriasis management.

Pair supplements with a balanced diet, regular movement, stress reduction techniques, and avoid triggers like alcohol or processed foods for the best results.

Lifestyle Tips to Complement Supplements For Psoriasis

While the right supplements for psoriasis can make a meaningful difference, pairing them with targeted lifestyle habits can help maximize results. Diet, hydration, and stress levels all play a direct role in inflammation and immune function, which are central to psoriasis management. By consistently making supportive choices around diet and lifestyle, you create an environment where your supplements can work more effectively and your skin has a better chance to heal and maintain balance.

Key lifestyle adjustments for psoriasis support:

  • Eat anti-inflammatory foods like fatty fish, berries, and leafy greens.
  • Stay hydrated to help flush out toxins and keep skin cells plump.
  • Limit alcohol, as it can trigger flare-ups in some people.
  • Manage stress with mindfulness or yoga, since stress is a known psoriasis trigger.

These lifestyle adjustments also help reduce common triggers that contribute to flare-ups. Prioritizing anti-inflammatory foods, staying well-hydrated, moderating alcohol intake, and managing stress can improve not only your skin’s condition but also your overall well-being. When these habits are combined with a daily supplement routine that helps enhance detoxification, minimize inflammation, and support gut restoration, they form a powerful, well-rounded strategy for long-term psoriasis relief.

Read also:

Sources: 

  1. Cleveland Clinic. (n.d.). Oxidative stress: Causes, symptoms & treatment. Cleveland Clinic. Retrieved August 12, 2025, from https://my.clevelandclinic.org/health/articles/oxidative-stress
  2. Wilchowski S. M. (2022). The Role of the Gut Microbiome in Psoriasis: From Pathogens to Pathology. The Journal of clinical and aesthetic dermatology, 15(3 Suppl 1), S25–S28 .  https://pmc.ncbi.nlm.nih.gov/articles/PMC8970207/ 
  3. Man, A. M., Orăsan, M. S., Hoteiuc, O. A., Olănescu-Vaida-Voevod, M. C., & Mocan, T. (2023). Inflammation and Psoriasis: A Comprehensive Review. International journal of molecular sciences, 24(22), 16095. https://doi.org/10.3390/ijms242216095
  4. Houghton, C. A., Fassett, R. G., & Coombes, J. S. (2016). Sulforaphane and Other Nutrigenomic Nrf2 Activators: Can the Clinician's Expectation Be Matched by the Reality?. Oxidative medicine and cellular longevity, 2016, 7857186. https://doi.org/10.1155/2016/7857186

Frequently Asked Question

Supplements for psoriasis are products containing nutrients and plant compounds that help manage symptoms by targeting inflammation, oxidative stress, and immune function. They’re designed to work alongside diet and lifestyle changes for more consistent relief. While not a cure, they can help reduce the frequency and severity of psoriasis flare-ups.

Yes, certain supplements have been clinically studied for their role in reducing inflammation and supporting skin health. Sulforaphane, omega-3 fatty acids, and vitamin D are among the most researched. Results depend on product quality, dosage, and consistent use.

Natural remedies for psoriasis often include anti-inflammatory supplements, stress reduction, and dietary changes. Sulforaphane, turmeric, and omega-3s are common choices. They work best when combined with a nutrient-rich diet and healthy habits.

No, supplements should not replace prescribed medications without your doctor’s approval. They can complement medical treatments and may help reduce side effects or flare-ups. Always coordinate supplement use with your healthcare provider.

High-quality, third-party tested supplements are generally safe for daily use when taken as directed. However, some ingredients may interact with medications, so it’s important to consult your doctor first. Consistency is key for seeing results.

Anyone experiencing recurring flare-ups or seeking to reduce reliance on topical treatments may benefit. They’re especially helpful for those who prefer a natural, whole-body approach. People with other inflammatory conditions may also find them useful.